| Week 1 | ||||
| Thu, Sep. 7 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DAL 31 at KC 36 | Final | KC Thaddeus Lewis 286 yds. | KC Jordan Morris 76 yds. | KC J.J. Reed 118 yds. |
| Sat, Sep. 9 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| STL 28 at MIA 16 | Final | STL Jayden Daniels 267 tds. | STL T.J. Logan 63 yds. | STL Kennedy Lewis 82 yds. |
| Sun, Sep. 10 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIL 33 at NY 6 | Final | MIL Breylin Smith 316 yds. | MIL Kay'Ron Adams 72 yds. | MIL Greg Chatham 150 yds. |
| ATL 28 at BRO 22 | Final | ATL Ryan Glassman 224 yds. | ATL Ryan Glassman 20 yds. | ATL Mike Martinez 81 yds. |
| TEN 9 at BAL 25 | Final | BAL Randy Carlysle 257 yds. | BAL Tim Harper 54 yds. | BAL Robert Gallo 78 yds. |
| PHI 25 at TB 20 | Final | PHI Kyle Reid 229 yds. | PHI Paul Perkins 49 yds. | PHI Jaydon Thompson 86 yds. |
| CAR 14 at PIT 8 | Final | CAR Steven Duncan 198 yds. | CAR Steven Duncan 33 yds. | CAR Xavier Kinney 70 yds. |
| SD 34 at IND 21 | Final | SD Douglas Knotts 339 yds. | SD Earl Wregget 65 yds. | SD Leonardo Hughes 138 yds. |
| BOS 16 at NO 20 | Final | NO Chris Coy 234 yds. | NO Austin Thomas 45 yds. | NO Jacob Mallory 66 yds. |
| CLE 26 at HOU 3 | Final | CLE De'Andre Johnson 281 yds. | CLE De'Andre Johnson 60 yds. | CLE Antonio Tucker 104 yds. |
| BUF 17 at COL 16 | Final | BUF Kyle Allen 213 yds. | BUF Justin Jonas 52 yds. | BUF Marvin MacDonald 73 yds. |
| CHI 20 at ARI 24 | Final | ARI Jon Fallon 156 yds. | ARI Jon Fallon 21 yds. | ARI Tanarius Greene 60 yds. |
| WAS 18 at LV 26 | Final | LV Brendan Cyr 217 yds. | LV Ise Smith 153 yds. | LV Jamal Weekes 77 yds. |
| DET 31 at CAL 30 | Final | DET Brandon Peters 268 yds. | DET Otis Harper 68 yds. | DET Patrick Allen 106 yds. |
| Mon, Sep. 11 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| SEA 27 at MIN 24 | Final | SEA Raymond Berry 271 yds. | SEA Tyler Lockett 61 yds. | SEA Anthony Jones 110 yds. |
| CLE 26 at HOU 3 | Final | CLE De'Andre Johnson 281 yds. | CLE De'Andre Johnson 60 yds. | CLE Antonio Tucker 104 yds. |
| Week 2 | ||||
| Thu, Sep. 14 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| SD 34 at MIN 28 | Final | SD Douglas Knotts 346 yds. | SD Earl Wregget 129 yds. | SD Kyi Wright 134 yds. |
| Sun, Sep. 17 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| ATL 27 at NY 25 | Final | ATL Ryan Glassman 268 yds. | ATL Tayvon Jacobs 40 yds. | ATL Mike Martinez 84 yds. |
| SEA 37 at BRO 31 | Final (ot) | SEA Raymond Berry 326 yds. | SEA Raymond Berry 44 yds. | SEA Tyler Lockett 112 yds. |
| PHI 27 at WAS 23 | Final | PHI Kyle Reid 296 yds. | PHI Paul Perkins 67 yds. | PHI Jaydon Thompson 93 yds. |
| LV 17 at BUF 41 | Final | BUF Kyle Allen 389 yds. | BUF Justin Jonas 110 yds. | BUF Marvin MacDonald 147 yds. |
| CLE 30 at CAR 16 | Final | CLE De'Andre Johnson 244 yds. | CLE De'Andre Johnson 36 yds. | CLE Antonio Tucker 71 yds. |
| TEN 28 at MIA 27 | Final | TEN Ben Bryant 227 yds. | TEN Sherwood Brown 86 yds. | TEN James Roe 69 yds. |
| CAL 30 at PIT 23 | Final | CAL Travis Wilson 339 yds. | CAL Micah Mason 118 yds. | CAL Jake Upton 134 yds. |
| LA 27 at IND 31 | Final | IND Scott Tolzner 251 yds. | IND D.J. Oats 53 yds. | IND Dontario Drummond 115 yds. |
| COL 28 at MIL 27 | Final | COL Brandon Morris 219 yds. | COL Omni Wells 62 yds. | COL Jayson Lee 78 yds. |
| BAL 28 at NO 20 | Final | BAL Randy Carlysle 266 yds. | BAL Randy Carlysle 47 yds. | BAL Tim Harper 103 yds. |
| TB 27 at STL 9 | Final | TB John Locke 265 yds. | TB Jay Dillon 77 yds. | TB Keyontae Johnson 97 yds. |
| CHI 8 at HOU 16 | Final | HOU Brett Smith 179 yds. | HOU Milo Hall 48 yds. | HOU Teo Redding 63 yds. |
| CIN 20 at ARI 26 | Final | ARI Jon Fallon 224 yds. | ARI Jon Fallon 23 yds. | ARI Tyler Simmons 70 yds. |
| KC 26 at BOS 3 | Final | KC Thaddeus Lewis 278 yds. | KC Jordan Morris 81 yds. | KC Kevin Kroger 126 yds. |
| Mon, Sep. 18 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DAL 30 at DET 26 | Final | DAL Adam Froman 276 yds. | DAL Chris L. Tucker 82 yds. | DAL Roy Roberts 109 yds. |
| Week 3 | ||||
| Thu, Sep. 21 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CIN 31 at TEN 13 | Final | CIN Kevin Hogan 265 yds. | CIN Kenyon Barnes 80 yds. | CIN J.J. Jefferson 126 yds. |
| Sun, Sep. 24 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| STL 20 at BRO 31 | Final | BRO Logan Fisher 254 yds. | BRO Jordan Ellis 71 yds. | BRO Edward Canterbury 92 yds. |
| DAL 20 at BAL 26 | Final | BAL Randy Carlysle 238 yds. | BAL Tim Harper 52 yds. | BAL Jonathan Adams 83 yds. |
| NY 17 at CAR 15 | Final | NY Ryan Gable 239 yds. | NY R.J. Cash 62 yds. | NY Draymond Blackshear 68 yds. |
| PHI 33 at CLE 20 | Final | PHI Kyle Reid 334 yds. | PHI Paul Perkins 176 yds. | PHI Jaydon Thompson 91 yds. |
| WAS 25 at ATL 6 | Final | WAS Austin McNiel 262 yds. | WAS Justin Hill 67 yds. | WAS Geno Lewis 66 yds. |
| TB 20 at PIT 23 | Final | PIT Tommy Reese 277 yds. | PIT Madre London 62 yds. | PIT Kirby Moore 88 yds. |
| NO 24 at MIN 21 | Final | NO Chris Coy 251 yds. | NO Austin Thomas 71 yds. | NO Jacob Mallory 80 yds. |
| MIA 56 at HOU 10 | Final | MIA Adam Murray 366 yds. | MIA Darnell Sullivan 122 yds. | MIA Devin Youngblood 156 yds. |
| DET 24 at COL 6 | Final | DET Brandon Peters 276 yds. | DET Otis Harper 65 yds. | DET Anthony Ratliff 84 yds. |
| MIL 18 at ARI 26 | Final | ARI Jon Fallon 224 yds. | ARI Jon Fallon 38 yds. | ARI Tyler Simmons 79 yds. |
| IND 20 at SEA 25 | Final | SEA Raymond Berry 248 yds. | SEA Raymond Berry 54 yds. | SEA Tyler Lockett 106 yds. |
| BOS 23 at LV 13 | Final | BOS Vance Becker 263 yds. | BOS Vance Becker 34 yds. | BOS Wesley Matthews 77 yds. |
| CHI 10 at LA 41 | Final | LA Rayce Dawson 360 yds. | LA Gary Brightwell 82 yds. | LA Taiwan Jones 142 yds. |
| SD 24 at CAL 31 | Final | CAL Travis Wilson 302 yds. | CAL Micah Mason 165 yds. | CAL Jake Upton 108 yds. |
| Mon, Sep. 25 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| KC 26 at BUF 17 | Final | KC Thaddeus Lewis 296 yds. | KC Jordan Morris 75 yds. | KC Kevin Kroger 88 yds. |
| Week 4 | ||||
| Thu, Sep. 28 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIL 20 at STL 34 | Final | STL Jayden Daniels 279 yds. | STL T.J. Logan 81 yds. | STL Kennedy Lewis 112 yds. |
| Sun, Oct. 1 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CLE 3 at NY 26 | Final | NY Ryan Gable 244 yds. | NY R.J. Cash 122 yds. | NY B.J. MacIntyre 104 yds. |
| CAR 28 at PHI 31 | Final | PHI Kyle Reid 277 yds. | PHI Paul Perkins 80 yds. | PHI Jaydon Thompson 129 yds. |
| NO 20 at ATL 7 | Final | NO Chris Coy 263 yds. | NO Austin Thomas 75 yds. | NO Jacob Mallory 91 yds. |
| CAL 44 at CHI 13 | Final | CAL Travis Wilson 325 yds. | CAL Micah Mason 176 yds. | CAL Jake Upton 141 yds. |
| LA 20 at HOU 26 | Final | HOU Brett Smith 234 yds. | HOU Milo Hall 71 yds. | HOU Teo Redding 78 yds. |
| COL 31 at ARI 28 | Final | COL Brandon Morris 278 yds. | COL Omni Wells 56 yds. | COL Jayson Lee 88 yds. |
| BRO 14 at SD 27 | Final | SD Douglas Knotts 293 yds. | SD Earl Wregget 143 yds. | SD Kyi Wright 98 yds. |
| DET 34 at MIA 6 | Final | DET Brandon Peters 304 yds. | DET Otis Harper 70 yds. | DET Anthony Ratliff 162 yds. |
| Mon, Oct. 2 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| PIT 10 at BUF 43 | Final | BUF Kyle Allen 337 yds. | BUF Justin Jonas 88 yds. | BUF Marvin MacDonald 109 yds. |
| Week 5 | ||||
| Thu, Oct. 5 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NY 23 at WAS 31 | Final | WAS Austin McNiel 255 yds. | WAS Justin Hill 73 yds. | WAS Marcus Kemp 122 yds. |
| Sun, Oct. 8 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TB 23 at BAL 10 | Final | TB John Locke 249 yds. | TB Jay Dillon 61 yds. | TB Keyontae Johnson 78 yds. |
| KC 27 at CAR 23 | Final | KC Thaddeus Lewis 267 yds. | KC Jordan Morris 52 yds. | KC Kevin Kroger 130 yds. |
| HOU 27 at CIN 36 | Final | CIN Kevin Hogan 328 yds. | CIN Kenyon Barnes 80 yds. | CIN J.J. Jefferson 156 yds. |
| ATL 28 at TEN 6 | Final | ATL Ryan Glassman 234 yds. | ATL Ryan Glassman 33 yds. | ATL Mike Martinez 76 yds. |
| IND 20 at CHI 40 | Final | CHI Quadry Jones 296 yds. | CHI Jalen Jackson 68 yds. | CHI Jayson Lee 213 yds. |
| DAL 24 at COL 17 | Final | DAL Adam Froman 263 yds. | DAL Chris L. Tucker 77 yds. | DAL Marlon Williams 141 yds. |
| DET 42 at SEA 24 | Final | DET Brandon Peters 306 yds. | DET Otis Harper 78 yds. | DET Anthony Ratliff 147 yds. |
| SD 28 at LV 12 | Final | SD Douglas Knotts 260 yd. | SD Earl Wregget 102 yds. | SD Leonardo Hughes 101 yds. |
| BUF 20 at MIN 26 | Final | MIN Thomas Kaye 233 yds. | MIN Charles Hyder 72 yds. | MIN Dominique Worthy 114 yds. |
| Mon, Oct. 9 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BOS 0 at STL 17 | Final | STL Jayden Daniels 228 yds. | STL T.J. Logan 69 yds. | STL Kennedy Lewis 67 yds. |
| Week 6 | ||||
| Thu, Oct. 12 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CIN 24 at PIT 22 | Final | CIN Kevin Hogan 266 yds. | CIN Kenyon Barnes 71 yds. | CIN J.J. Jefferson 111 yds. |
| Sun, Oct. 15 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TEN 20 at BRO 24 | Final | BRO Logan Fisher 245 yds. | BRO Jordan Ellis 67 yds. | BRO Edward Canterbury 84 yds. |
| WAS 10 at MIA 42 | Final | MIA Adam Murray 361 yds. | MIA Charles Hyder 89 yds. | MIA Jamal Weekes 148 yds. |
| BOS 6 at BAL 26 | Final | BAL Randy Carlysle 233 yds. | BAL Randy Carlysle 36 yds. | BAL Jonathan Adams 87 yds. |
| TB 6 at CLE 21 | Final | CLE De'Andre Johnson 229 yds. | CLE De'Andre Johnson 45 yds. | CLE Pharoah Brown 76 yds. |
| ARI 17 at IND 12 | Final | ARI Jon Fallon 231 yds. | ARI Tyler Simmons 73 yds. | ARI Tyler Simmons 66 yds. |
| SEA 28 at MIL 14 | Final | SEA Raymond Berry 242 yds. | SEA Anthony Jones 51 yds. | SEA Devin Gray 78 yds. |
| NO 13 at KC 17 | Final | KC Thaddeus Lewis 197 yds. | KC Jordan Morris 58 yds. | KC Kevin Kroger 65 yds. |
| LV 22 at LA 25 | Final | LA Rayce Dawson 249 yds. | LA Gary Brightwell 70 yds. | LA Jordan Thomas 82 yds. |
| PHI 14 at DAL 23 | Final | DAL Adam Froman 277 yds. | DAL Chris L. Tucker 67 yds. | DAL Roy Roberts 114 yds. |
| Mon, Oct. 16 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIN 19 at CAL 17 | Final | MIN Thomas Kaye 264 yds. | CAL Micah Mason 92 yds. | MIN Dominique Worthy 125 yds. |
| Week 7 | ||||
| Thu, Oct. 19 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BRO 23 at BAL 35 | Final | BAL Randy Carlysle 365 yds. | BAL Tim Harper 76 yds. | BAL Robert Gallo 114 yds. |
| Sun, Oct. 22 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| WAS 7 at PHI 26 | Final | PHI Kyle Reid 264 yds. | PHI Paul Perkins 77 yds. | PHI Jaydon Thompson 108 yds. |
| NO 20 at CAR 16 | Final | NO Chris Coy 229 yds. | NO Austin Thomas 77 yds. | NO Jailyn Marshall 81 yds. |
| MIA 40 at TB 13 | Final | MIA Adam Murray 360 yds. | MIA Charles Hyder 115 yds. | MIA Jamal Weekes 162 yds. |
| KC 23 at ATL 26 | Final | ATL Ryan Glassman 261 yds. | ATL Tayvon Jacobs 33 yds. | ATL Mike Martinez 76 yds. |
| NY 14 at CLE 28 | Final | CLE De'Andre Johnson 247 yds. | CLE De'Andre Johnson 56 yds. | CLE Pharoah Brown 124 yds. |
| DET 39 at IND 38 | Final | DET Brandon Peters 312 yds. | DET Otis Harper 61 yds. | DET Patrick Allen 111 yds. |
| MIL 20 at CHI 23 | Final | CHI Quadry Jones 231 yds. | CHI Jalen Jackson 85 yds. | CHI Jayson Lee 80 yds. |
| BOS 34 at TEN 20 | Final | BOS Vance Becker 252 yds. | BOS Wesley Matthews 42 yds. | BOS Wesley Matthews 88 yds. |
| HOU 20 at STL 31 | Final | STL Jayden Daniels 239yds. | STL T.J. Logan 82 yds. | STL Kennedy Lewis 104 yds. |
| COL 9 at DAL 20 | Final | DAL Adam Froman 272 yds. | DAL Chris L. Tucker 70 yds. | DAL Roy Roberts 144 yds. |
| ARI 10 at SEA 21 | Final | SEA Raymond Berry 233 yds. | SEA Raymond Berry 55 yds. | SEA Anthony Jones 86 yds. |
| LA 20 at CAL 21 | Final | CAL Travis Wilson 314 yds. | CAL Micah Mason 136 yds. | CAL Jake Upton 124 yds. |
| LV 13 at SD 30 | Final | SD Douglas Knotts 310 yds. | SD Earl Wregget 124 yds. | SD Leonardo Hughes 128 yds. |
| MIN 28 at BUF 27 | Final | MIN Thomas Kaye 249 yds. | MIN Darnell Sullivan 50 yds. | MIN Dominique Worthy 112yds. |
| Mon, Oct. 23 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| PIT 28 at CIN 30 | Final | CIN Kevin Hogan 308 yds. | CIN Kenyon Barnes 74 yds. | CIN J.J. Jefferson 121 yds. |
| Week 8 | ||||
| Thu, Oct. 26 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BAL 27 at BOS 3 | Final | BAL Randy Carlysle 255 yds. | BAL Tim Harper 51 yds. | BAL Robert Gallo 109 yds. |
| Sun, Oct. 29 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CLE 23 at WAS 18 | Final | CLE De'Andre Johnson 263 yds. | CLE De'Andre Johnson 42 yds. | CLE Antonio Tucker 112 yds. |
| HOU 17 at MIA 31 | Final | MIA Adam Murray 287 yds. | MIA Charles Hyder 66 yds, | MIA Jamal Weekes 143 yds. |
| STL 20 at TB 10 | Final | STL Jayden Daniels 237 yds. | STL T.J. Logan 56 yds. | STL Kennedy Lewis 78 yds. |
| MIN 23 at PIT 17 | Final | MIN Thomas Kaye 250 yds. | MIN Darnell Sullivan 48 yds. | MIN Domino Jenkins 82 yds. |
| BUF 20 at CIN 28 | Final | CIN Kevin Hogan 284 yds. | CIN Kenyon Barnes 64 yds. | CIN J.J. Jefferson 119 yds. |
| CHI 10 at DET 45 | Final | DET Brandon Peters 414 yds. | DET Otis Harper 122 yds. | DET Anthony Ratliff 210 yds. |
| IND 8 at MIL 17 | Final | MIL Breylin Smith 198 yds. | MIL Kay'Ron Adams 85 yds. | MIL Matt Adams 73 yds. |
| BRO 23 at TEN 20 | Final | BRO Logan Fisher 221 yds. | BRO Jordan Ellis 58 yds. | BRO Edward Canterbury 116 yds. |
| CAR 20 at NO 35 | Final | NO Chris Coy 318 yds. | NO Austin Thomas 77 yds. | NO Jacob Mallory 93 yds. |
| ATL 23 at KC 17 | Final | ATL Ryan Glassman 254 yds. | ATL Tayvon Jacobs 36 yds. | ATL Tayvon Jacobs 78 yds. |
| CAL 21 at LV 14 | Final | CAL Travis Wilson 265 yds. | CAL Micah Mason 128 yds. | CAL Jake Upton 92 yds. |
| COL 24 at SEA 20 | Final | COL Brandon Morris 260 yds. | COL Omni Wells 74 yds. | COL Omni Wells 90 yds. |
| LA 20 at SD 34 | Final | SD Douglas Knotts 332 yds. | SD Earl Wregget 116 yds. | SD Leonardo Hughes 114 yds. |
| PHI 28 at NY 24 | Final | PHI Kyle Reid 260 yds. | PHI Paul Perkins 68 yds. | PHI Jaydon Thompson 106 yds. |
| Mon, Oct. 30 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DAL 48 at ARI 7 | Final | DAL Adam Froman 365 yds. | DAL Chris L. Tucker 127 yds. | DAL Roy Roberts 169 yds. |
| Week 9 | ||||
| Thu, Nov. 2 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DET 43 at MIL 21 | Final | DET Brandon Peters 396 yds. | DET Otis Harper 65 yds. | DET Anthony Ratliff 174 yds. |
| Sun, Nov. 5 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIA 17 at BOS 19 | Final | BOS Vance Becker 211 yds. | BOS Vance Becker 32 yds. | BOS Wesley Matthews 61 yds. |
| NO 30 at NY 6 | Final | NO Chris Coy 387 yds. | NO Austin Thomas 87 yds. | NO Jailyn Marshall 135 yds. |
| MIN 31 at BRO 28 | Final | MIN Thomas Kaye 228 yds. | MIN Darnell Sullivan 63 yds. | MIN Kris Thompkins 110 yds. |
| CAR 20 at WAS 28 | Final | WAS Austin McNiel 264 yds. | WAS Justin Hill 56 yds. | WAS Geno Lewis 86 yds. |
| LV 26 at TB 17 | Final | LV Brendan Cyr 254 yds. | LV Ise Smith 118 yds. | LV Titus Dorsey 122 yds. |
| PHI 28 at ATL 14 | Final | PHI Kyle Reid 259 yds. | PHI Paul Perkins 72 yds. | PHI Jaydon Thompson 161 yds. |
| DAL 26 at IND 7 | Final | DAL Adam Froman 267 yds. | DAL Chris L. Tucker 68 yds. | DAL Roy Roberts 118 yds. |
| COL 23 at CHI 17 | Final | COL Brandon Morris 266 yds. | COL Omni Wells 115 yds. | COL Omni Wells 92 yds. |
| STL 26 at TEN 20 | Final | STL Jayden Daniels 261 yds. | STL T.J. Logan 59 yds. | STL Kennedy Lewis 113 yds. |
| CLE 20 at KC 24 | Final | KC Thaddeus Lewis 281 yds. | KC Jordan Morris 121 yds. | KC Kevin Kroger 106 yds. |
| BAL 33 at HOU 31 | Final | BAL Randy Carlysle 248 yds. | BAL Tim Harper 67 yds. | BAL Robert Gallo 88 yds. |
| SEA 13 at ARI 6 | Final | SEA Raymond Berry 172 yds. | SEA Raymond Berry 40 yds. | SEA Anthony Jones 67 yds. |
| PIT 20 at LA 3 | Final | PIT Tommy Reese 251 yds.nbsp; | PIT Madre London 77 yds. | PIT Marcus Floyd 98 yds. |
| BUF 20 at SD 31 | Final | SD Douglas Knotts 297 yds. | SD Earl Wregget 119 yds. | SD Leonardo Hughes 342 yds. |
| Mon, Nov. 6 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CIN 27 at CAL 23 | Final | CIN Kevin Hogan 268 yds. | CIN Kenyon Barnes 81 yds. | CIN J.J. Jefferson 120 yds. |
| Week 10 | ||||
| Thu, Nov. 9 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| SEA 20 at DAL 46 | Final | DAL Adam Froman 341 yds. | DAL Chris L. Tucker 119 yds. | DAL Roy Roberts 134 yds. |
| Sun, Nov. 12 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TEN 26 at CAR 13 | Final | TEN Ben Bryant 241 yds. | TEN Sherwood Brown 63 yds. | TEN James Roe 78 yds. |
| BRO 17 at TB 20 | Final | TB John Locke 227 yds. | TB Jay Dillon 67 yds. | TB Keyontae Johnson 80 yds. |
| KC 34 at PHI 30 | Final | KC Thaddeus Lewis 314 yds. | KC Jordan Morris 125 yds. | KC J.J. Reed 163 yds. |
| CHI 21 at CLE 23 | Final | CLE De'Andre Johnson 262 yds. | CLE De'Andre Johnson 36 yds. | CLE Antonio Tucker 114 yds. |
| ARI 17 at DET 41 | Final | DET Brandon Peters 349 yds. | DET Otis Harper 62 yds. | DET Anthony Ratliff 151 yds. yds. |
| ATL 12 at CIN 21 | Final | CIN Kevin Hogan 266 yds. | CIN Kenyon Barnes 70 yds. | CIN J.J. Jefferson 136 yds. |
| WAS 28 at NO 20 | Final | WAS Austin McNiel 253 yds. | WAS Justin Hill 74 yds. | WAS Marcus Kemp 94 yds. |
| NY 23 at STL 17 | Final | NY Ryan Gable 270 yds. | NY R.J. Cash 82 yds. | NY Draymond Blackshear 101 yds. |
| BOS 6 at HOU 22 | Final | HOU Brett Smith 237 yds. | HOU Milo Hall 66 yds. | HOU Teo Redding 85 yds. |
| IND 13 at COL 27 | Final | COL Brandon Morris 224 yds. | COL Omni Wells 59 yds. | COL Omni Wells 72 yds. |
| MIN 26 at LV 9 | Final | MIN Thomas Kaye 228 yds. | MIN Darnell Sullivan 63 yds. | MIN Dominique Worthy 111 yds. |
| MIL 19 at LA 26 | Final | LA Rayce Dawson 253 yds. | LA Gary Brightwell 66 yds. | LA Taiwan Jones 121 yds. |
| PIT 36 at SD 35 | Final | PIT Tommy Reese 367 yds. | PIT Madre London 148 yds. | PIT Marcus Floyd 139 yds. |
| CAL 42 at BUF 24 | Final | CAL Travis Wilson 344 yds. | CAL Micah Mason 178 yds. | CAL Jake Upton 126 yds. |
| Mon, Nov. 13 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIA 30 at BAL 17 | Final | MIA Adam Murray 286 yds. | MIA Charles Hyder 81 yds. | MIA Jamal Weekes 123 yds. |
| Week 11 | ||||
| Thu, Nov. 16 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DAL 30 at BUF 22 | Final | DAL Adam Froman 281 yds. | DAL Chris L. Tucker 77 yds. | DAL Marlon Williams 118 yds. |
| Sun, Nov. 19 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BAL 21 at BRO 20 | Final | BAL Randy Carlysle 246 yds. | BAL Tim Harper 63 yds. | BAL Robert Gallo 78 yds. |
| ARI 17 at BOS 23 | Final | BOS Vance Becker 227 yds. | BOS Vance Becker 36 yds. | BOS Wesley Matthews 88 yds. |
| KC 30 at WAS 21 | Final | KC Thaddeus Lewis 254 yds. | KC Jordan Morris 110 yds. | KC Andrew Pierce 76 yds. |
| ATL 20 at CAR 7 | Final | ATL Ryan Glassman 229 yds. | ATL Tayvon Jacobs 24 yds. | ATL Tayvon Jacobs 67 yds. |
| TEN 24 at TB 18 | Final | TEN Ben Bryant 266 yds. | TEN Sherwood Brown 73 yds. | TEN James Roe 81 yds. |
| MIA 20 at CLE 30 | Final | CLE De'Andre Johnson 252 yds. | CLE De'Andre Johnson 30 yds. | CLE Theo Howard 84 yds. |
| IND 26 at DET 31 | Final | DET Brandon Peters 247 yds. | DET Otis Harper 58 yds. | DET Patrick Allen 114 yds. |
| CHI 27 at MIL 31 | Final | MIL Breylin Smith 256 yds. | MIL Kay'Ron Adams 77 yds. | MIL Greg Chatham 87 yds. |
| CIN 13 at MIN 23 | Final | MIN Thomas Kaye 226 yds. | MIN Darnell Sullivan 87 yds. | MIN Dominique Worthy 74 yds. |
| STL 27 at HOU 20 | Final | STL Jayden Daniels 253 yds. | STL T.J. Logan 61 yds. | STL Kennedy Lewis 92 yds. |
| PIT 24 at COL 7 | Final | PIT Tommy Reese 236 yds. | PIT Madre London 60 yds. | PIT Madre London 78 yds. |
| NY 22 at SEA 16 | Final | NY Ryan Gable 226 yds. | NY R.J. Cash 70 yds. | NY Draymond Blackshear 111 yds. |
| LV 12 at CAL 22 | Final | CAL Travis Wilson 221 yds. | CAL Micah Mason 112 yds. | CAL Jake Upton 82 yds. |
| SD 20 at LA 22 | Final | LA Rayce Dawson 228 yds. | LA Gary Brightwell 83 yds. | LA Jayar Jackson 90 yds. |
| Mon, Nov. 20 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| PHI 26 at NO 15 | Final | PHI Kyle Reid 244 yds. | PHI Paul Perkins 81 yds. | PHI Jaydon Thompson 104 yds. |
| Week 12 | ||||
| Thu, Nov. 23 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| KC 29 at DET 22 | Final | KC Thaddeus Lewis 266 yds. | KC Jordan Morris 108 yds. | KC Andrew Pierce 113 yds. |
| MIN 23 at DAL 41 | Final | DAL Adam Froman 279 yds. | DAL Chris L. Tucker 83 yds. | DAL Roy Roberts 172 yds. |
| PIT 28 at SEA 23 | Final | PIT Tommy Reese 232 yds. | PIT Madre London 78 yds. | PIT Madre London 88 yds. |
| Fri, Nov. 24 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NY 26 at SD 21 | Final | NY Ryan Gable 273 yds. | NY R.J. Cash 119 yds. | NY B.J. MacIntyre 110 yds. |
| Sat, Nov. 25 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CAL 38 at MIA 31 | Final | CAL Travis Wilson 259 yds. | CAL Micah Mason 164 yds. | CAL Jake Upton 122 yds. |
| Sun, Nov. 26 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TB 13 at BOS 7 | Final | TB John Locke 197 yds. | TB Jay Dillon 58 yds. | TB Otis Glendale 69 yds. |
| ARI 20 at BUF 26 | Final | BUF Kyle Allen 267 yds. | BUF Justin Jonas 91 yds. | BUF Marvin MacDonald 108 yds. |
| HOU 21 at PHI 27 | Final | PHI Kyle Reid 276 yds. | PHI Paul Perkins 71 yds. | PHI Jaydon Thompson 126 yds. |
| BRO 16 at CAR 9 | Final | BRO Logan Fisher 221 yds. | BRO Jordan Ellis 66 yds. | BRO Edward Canterbury 73 yds. |
| IND 23 at WAS 15 | Final | IND Scott Tolzner 230 yds. | IND D.J. Oats 61 yds. | IND Dontario Drummond 78 yds. |
| ATL 31 at CHI 12 | Final | ATL Ryan Glassman 229 yds. | ATL Ryan Glassman 33 yds. | ATL Mike Martinez 70 yds. |
| COL 34 at CIN 18 | Final | COL Brandon Morris 227 yds. | COL Omni Wells 104 yds. | COL Demarcus Robinson 89 yds. |
| LV 13 at MIL 20 | Final | MIL Breylin Smith 223 yds. | MIL Kay'Ron Adams 89 yds. | MIL Greg Chatham 100 yds. |
| TEN 24 at LA 17 | Final | TEN Ben Bryant 212 yds. | TEN Sherwood Brown 74 yds. | TEN James Roe 98 yds. |
| BAL 23 at STL 17 | Final | BAL Randy Carlysle 244 yds. | BAL Tim Harper 61 yds. | BAL Jonathan Adams 89 yds. |
| Mon, Nov. 27 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NO 14 at CLE 20 | Final | CLE De'Andre Johnson 267 yds. | CLE De'Andre Johnson 22 yds. | CLE Antonio Tucker 77 yds. |
| Week 13 | ||||
| Thu, Nov. 30 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIL 22 at DET 39 | Final | DET Brandon Peters 328 yds. | DET Otis Harper 77 yds. | DET Anthony Ratliff 115 yds. |
| Sat, Dec. 2 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BRO 20 at MIA 31 | Final | MIA Adam Murray 278 yds. | MIA Charles Hyder 61 yds. | MIA Jamal Weekes 109 yds. |
| Sun, Dec. 3 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TEN 27 at BOS 13 | Final | TEN Ben Bryant 256 yds. | TEN Sherwood Brown 73 yds. | TEN James Roe 92 yds. |
| WAS 24 at NY 12 | Final | WAS Austin McNiel 219 yds. | WAS Justin Hill 66 yds. | WAS Marcus Kemp 74 yds. |
| CLE 28 at PHI 26 | Final | CLE De'Andre Johnson 263 yds. | CLE De'Andre Johnson 47 yds. | CLE Antonio Tucker 97 yds. |
| HOU 20 at TB 24 | Final | TB John Locke 220 yds. | TB Jay Dillon 56 yds. | TB Otis Glendale 73 yds. |
| COL 15 at ATL 31 | Final | ATL Ryan Glassman 249 yds. | ATL Tayvon Jacobs 27 yds. | ATL Mike Martinez 108 yds. |
| BUF 26 at PIT 13 | Final | BUF Kyle Allen 239 yds. | BUF Justin Jonas 59 yds. | BUF Nick Hill 78 yds. |
| CHI 18 at IND 24 | Final | IND Scott Tolzner 252 yds. | IND D.J. Oats 65 yds. | IND Tre Tipton 76 yds. |
| SEA 20 at NO 17 | Final | SEA Raymond Berry 223 yds. | SEA Raymond Berry 46 yds. | SEA Anthony Jones 81 yds. |
| SD 27 at STL 23 | Final | SD Douglas Knotts 282 yds. | SD Earl Wregget 114 yds. | SD Kyi Wright 109 yds. |
| CAR 13 at KC 36 | Final | KC Thaddeus Lewis 328 yds. | KC Jordan Morris 123 yds. | KC J.J. Reed 141 yds. |
| ARI 23 at DAL 47 | Final | DAL Adam Froman 274 yds. | DAL Chris L. Tucker 163 yds. | DAL Roy Roberts 148 yds. |
| CIN 17 at LV 27 | Final | LV Brendan Cyr 221 yds. | LV Ise Smith 126 yds. | LV Titus Dorsey 74 yds. |
| BAL 17 at CAL 33 | Final | CAL Travis Wilson 296 yds. | CAL Micah Mason 167 yds. | CAL Jake Upton 115 yds. |
| Mon, Dec. 4 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| LA 26 at MIN 17 | Final | LA Rayce Dawson 260 yds. | LA Gary Brightwell 86 yds. | LA Jordan Thomas 125 yds. |
| Week 14 | ||||
| Thu, Dec. 7 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| SD 20 at CIN 34 | Final | CIN Matt Berkley 285 yds. | CIN Kenyon Barnes 126 yds. | CIN J.J. Jefferson 98 yds. |
| Sat, Dec. 9 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NY 20 at KC 17 | Final | NY Ryan Gable 224 yds. | NY R.J. Cash 113 yds. | NY Draymond Blackshear 82 yds. |
| Sun, Dec. 10 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BRO 30 at BOS 7 | Final | BRO Logan Fisher 325 yds. | BRO Jordan Ellis 117 yds. | BRO Keith Davis 161 yds. |
| TB 23 at MIA 31 | Final | MIA Adam Murray 248 yds. | MIA Charles Hyder 112 yds. | MIA Jamal Weekes 140 yds. |
| LV 23 at PIT 17 | Final | LV Brendan Cyr 218 yds. | LV Ise Smith 156 yds. | LV Kyle Carter 78 yds. |
| CAR 10 at IND 31 | Final | IND Scott Tolzner 227 yds. | IND D.J. Oats 83 yds. | IND Dontario Drummond 122 yds. |
| SEA 20 at CHI 32 | Final | CHI Quadry Jones 261 yds. | CHI Jalen Jackson 36 yds. | CHI Jayson Lee 104 yds. |
| ATL 25 at NO 27 | Final | NO Chris Coy 218 yds. | NO Austin Thomas 60 yds. | NO Jacob Mallory 84 yds. |
| STL 0 at MIN 3 | Final | MIN Thomas Kaye 152 yds. | MIN Darnell Sullivan 45 yds. | MIN Domino Jenkins 70 yds. |
| HOU 6 at TEN 20 | Final | TEN Ben Bryant 215 yds. | TEN Sherwood Brown 65 yds. | TEN Sherwood Brown 77 yds. |
| MIL 21 at DAL 41 | Final | DAL Adam Froman 327 yds. | DAL Chris L. Tucker 82 yds. | DAL Roy Roberts 143 yds. |
| WAS 20 at ARI 14 | Final | WAS Austin McNiel 224 yds. | WAS Justin Hill 65 yds. | WAS Justin Hill 68 yds. |
| CLE 21 at COL 27 | Final | COL Brandon Morris 262 yds. | COL Omni Wells 74 yds. | COL Demarcus Robinson 73 yds. |
| CAL 28 at LA 14 | Final | CAL Travis Wilson 306 yds. | CAL Micah Mason 186 yds. | CAL Courtney Smith 126 yds. |
| DET 33 at PHI 13 | Final | DET Brandon Peters 315 yds. | DET Otis Harper 87 yds. | DET Anthony Ratliff 119 yds. |
| Mon, Dec. 11 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BUF 26 at BAL 21 | Final | BUF Kyle Allen 279 yds. | BUF Justin Jonas 87 yds. | BUF Nick Hill 104 yds. |
| Week 15 | ||||
| Thu, Dec. 14 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BRO 0 at KC 31 | Final | KC Thaddeus Lewis 293 yds. | KC Jordan Morris 125 yds. | KC Kevin Kroger 112 yds. |
| Sat, Dec. 16 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| STL 13 at PHI 28 | Final | PHI Kyle Reid 284 yds. | PHI Paul Perkins 92 yds. | PHI Jaydon Thompson 107 yds. |
| Sun, Dec. 17 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TB 27 at NY 24 | Final | TB John Locke 236 yds. | TB Jay Dillon 74 yds. | TB Otis Glendale 81 yds. |
| ARI 7 at CAR 9 | Final | CAR Steven Duncan 169 yds. | CAR Steven Duncan 31 yds. | CAR Quentin Washington 66 yds. |
| BAL 23 at ATL 7 | Final | BAL Randy Carlysle 298 yds. | BAL Randy Carlysle 92 yds. | BAL Jonathan Adams 118 yds. |
| HOU 20 at WAS 16 | Final | HOU Brett Smith 229 yds. | HOU Milo Hall 68 yds. | HOU Teo Redding 87 yds. |
| MIA 33 at BUF 31 | Final | MIA Adam Murray 339 yds. | MIA Charles Hyder 165 yds. | MIA Jamal Weekes 144 yds. |
| NO 26 at TEN 23 | Final (ot) | NO Chris Coy 226 yds. | NO Austin Thomas 51 yds. | NO Jacob Mallory 78 yds. |
| CHI 25 at DAL 17 | Final | CHI Quadry Jones 213 yds. | CHI Jalen Jackson 67 yds. | CHI Jayson Lee 86 yds. |
| SEA 13 at COL 21 | Final | COL Brandon Morris 212 yds. | COL Omni Wells 80 yds. | COL Demarcus Robinson 77 yds. |
| DET 41 at LV 10 | Final | DET Brandon Peters 341 yds. | DET Otis Harper 76 yds. | DET Anthony Ratliff 122 yds. |
| IND 10 at CAL 34 | Final | CAL Travis Wilson 251 yds. | CAL Micah Mason 147 yds. | CAL Jake Upton 115 yds. |
| MIL 24 at SD 7 | Final | MIL Breylin Smith 214 yds. | MIL Kay'Ron Adams 68 yds. | MIL Matt Adams 79 yds. |
| CLE 28 at LA 26 | Final | CLE De'Andre Johnson 283 yds. | CLE De'Andre Johnson 32 yds. | CLE Pharoah Brown 80 yds. |
| PIT 20 at BOS 6 | Final | PIT Tommy Reese 206 yds. | PIT Madre London 63 yds. | PIT Marcus Floyd 67 yds. |
| Mon, Dec. 18 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIN 26 at CIN 29 | Final | CIN Matt Berkley 277 yds. | CIN Kenyon Barnes 83 yds. | CIN Tre Ellis 108 yds. |
| Week 16 | ||||
| Thu, Dec. 21 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NO 20 at MIL 33 | Final | MIL Breylin Smith 332 yds. | MIL Kay'Ron Adams 122 yds. | MIL Greg Chatham 141 yds. |
| Fri, Dec. 22 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DAL 30 at PIT 33 | Final | PIT Tommy Reese 277 yds. | PIT Madre London 103 yds. | PIT Madre London 115 yds. |
| Sat, Dec. 23 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| LV 18 at CHI 27 | Final | CHI Quadry Jones 263 yds. | CHI Jalen Jackson 72 yds. | CHI Jayson Lee 94 yds. |
| BUF 23 at LA 31 | Final | LA Rayce Dawson 296 yds. | LA Gary Brightwell 129 yds. | LA Jayar Jackson 118 yds. |
| KC 17 at BAL 34 | Final | BAL Randy Carlysle 256 yds. | BAL Tim Harper 64 yds. | BAL Jonathan Adams 116 yds. |
| Sun, Dec. 24 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CAR 17 at BOS 20 | Final | BOS Vance Becker 214 yds. | BOS Wesley Matthews 27 yds. | BOS Wesley Matthews 78 yds. |
| HOU 7 at BRO 20 | Final | BRO Logan Fisher 265 yds. | BRO Jordan Ellis 106 yds. | BRO Edward Canterbury 118 yds. |
| STL 10 at WAS 20 | Final | WAS Austin McNiel 242 yds. | WAS Justin Hill 63 yds. | WAS Geno Lewis 95 yds. |
| IND 13 at TB 21 | Final | TB John Locke 228 yds. | TB Jay Dillon 54 yds. | TB Otis Glendale 82 yds. |
| ATL 22 at CLE 17 | Final | ATL Ryan Glassman 235 yds. | ATL Tayvon Jacobs 33 yds. | ATL Mike Martinez 75 yds. |
| COL 20 at TEN 28 | Final | TEN Ben Bryant 261 yds. | TEN Sherwood Brown 70 yds. | TEN James Roe 87 yds. |
| MIN 19 at ARI 22 | Final | ARI Jon Fallon 213 yds. | ARI Jon Fallon 51 yds. | ARI Tyler Simmons 76 yds. |
| MIA 31 at NY 9 | Final | MIA Adam Murray 302 yds. | MIA Charles Hyder 103 yds. | MIA Jamal Weekes 154 yds. |
| Mon, Dec. 25 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| SEA 23 at CIN 15 | Final | SEA Raymond Berry 224 yds. | SEA Raymond Berry 53 yds. | SEA Anthony Jones 80 yds. |
| SD 24 at DET 32 | Final | DET Brandon Peters 308 yds. | DET Otis Harper 72 yds. | DET Anthony Ratliff 121 yds. |
| PHI 13 at CAL 24 | Final | CAL Travis Wilson 262 yds. | CAL Micah Mason 127 yds. | CAL Micah Mason 118 yds. |
| Week 17 | ||||
| Thu, Dec. 28 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TEN 12 at KC 20 | Final | KC Thaddeus Lewis 231 yds. | KC Jordan Morris 112 yds. | KC Andrew Pierce 78 yds. |
| Fri, Dec. 29 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NO 22 at BRO 17 | Final | NO Chris Coy 225 yds. | NO Austin Thomas 76 yds. | NO Jacob Mallory 83 yds. |
| Sat, Dec. 30 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CLE 26 at STL 24 | Final | CLE De'Andre Johnson 236 yds. | CLE De'Andre Johnson 24 yds. | CLE Antonio Tucker 90 yds. |
| LA 20 at DET 19 | Final | LA Rayce Dawson 283 yds. | LA Gary Brightwell 62 yds. | LA Jordan Thomas 162 yds. |
| PHI 20 at MIA 31 | Final | MIA Adam Murray 226 yds. | MIA Charles Hyder 69 yds. | MIA Jamal Weekes 114 yds. |
| Sun, Dec. 31 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CAR 0 at BAL 56 | Final | BAL Randy Carlysle 429 yds. | BAL Tim Harper 88 yds. | BAL Jonathan Adams 157 yds. |
| WAS 17 at TB 21 | Final | TB John Locke 223 yds. | TB Jay Dillon 57 yds. | TB Otis Glendale 93 yds. |
| BOS 17 at ATL 9 | Final | BOS Vance Becker 209 yds. | BOS Vance Becker 36 yds. | BOS Wesley Matthews 87 yds. |
| ARI 12 at PIT 20 | Final | PIT Tommy Reese 219 yds. | PIT Madre London 105 yds. | PIT Madre London 77 yds. |
| CAL 30 at MIL 21 | Final | CAL Travis Wilson 287 yds. | CAL Micah Mason 169 yds. | CAL Jake Upton 102 yds. |
| COL 13 at MIN 21 | Final | MIN Thomas Kaye 233 yds. | MIN Darnell Sullivan 77 yds. | MIN Dominique Worthy 84 yds. |
| NY 13 at HOU 20 | Final | HOU Brett Smith 226 yds. | HOU Milo Hall 87 yds. | HOU Jordan Higgins 75 yds. |
| IND 23 at LV 8 | Final | IND Scott Tolzner 259 yds. | IND D.J. Oats 54 yds. | IND Dontario Drummond 111 yds. |
| CHI 30 at SD 14 | Final | CHI Quadry Jones 262 yds. | CHI Jalen Jackson 51 yds. | CHI Jalen Jackson 126 yds |
| CIN 12 at DAL 20 | Final | DAL Adam Froman 268 yds. | DAL Chris L. Tucker 43 yds. | DAL Roy Roberts 171 yds. |
| Mon, Jan. 1 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BUF 27 at SEA 22 | Final | BUF Kyle Allen 261 yds. | BUF Justin Jonas 57 yds. | BUF Nick Hill 108 yds. |
| Week 18 | ||||
| Thu, Jan. 4 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| KC 20 at NO 12 | Final | KC Thaddeus Lewis 224 yds. | KC Jordan Morris 63 yds. | KC Devin Ross 75 yds. |
| Fri, Jan. 5 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NY 26 at PHI 10 | Final | NY Ryan Gable 260 yds. | NY R.J. Cash 148 yds. | NY B.J. MacIntyre 122 yds. |
| Sat, Jan. 6 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| BOS 3 at BRO 17 | Final | BRO Logan Fisher 215 yds. | BRO Jordan Ellis 69 yds. | BRO Edward Canterbury 81 yds. |
| MIA 28 at STL 20 | Final | MIA Adam Murray 244 yds. | MIA Charles Hyder 78 yds. | MIA Jamal Weekes 113 yds. |
| CIN 20 at BUF 34 | Final | BUF Kyle Allen 261 yds. | BUF Justin Jonas 70 yds. | BUF Marvin MacDonald 124 yds. |
| DAL 38 at SEA 23 | Final | DAL Adam Froman 305 yds. | DAL Chris L. Tucker 87 yds. | DAL Roy Roberts 128 yds. |
| Sun, Jan. 7 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| WAS 10 at CLE 0 | Final | WAS Austin McNiel 191 yds. | WAS Justin Hill 52 yds. | WAS Justin Hill 67 yds. |
| CAR 21 at ATL 17 | Final | CAR Steven Duncan 220 yds. | CAR Steven Duncan 47 yds. | CAR Ollie Harden 63 yds. |
| MIL 24 at IND 20 | Final | MIL Breylin Smith 256 yds. | MIL Kay'Ron Adams 89 yds. | MIL Greg Chatham 93 yds. |
| DET 30 at CHI 20 | Final | DET Brandon Peters 313 yds. | DET Otis Harper 60 yds. | DET Anthony Ratliff 149 yds. |
| BAL 20 at TEN 22 | Final | TEN Ben Bryant 217 yds. | TEN Sherwood Brown 156 yds. | TEN James Roe 76 yds. |
| PIT 23 at MIN 10 | Final | PIT Tommy Reese 228 yds. | PIT Madre London 113 yds. | PIT Marcus Floyd 91 yds. |
| TB 18 at HOU 9 | Final | TB John Locke 219 yds. | TB Jay Dillon 59 yds. | TB Otis Glendale 76 yds. |
| ARI 20 at COL 9 | Final | ARI Jon Fallon 214 yds. | ARI Jon Fallon 43 yds. | ARI Tyler Simmons 66 yds. |
| LA 21 at LV 20 | Final | LA Rayce Dawson 262 yds. | LA Gary Brightwell 88 yds. | LA Jayar Jackson 84 yds. |
| CAL 20 at SD 13 | Final | CAL Travis Wilson 217 yds. | CAL Micah Mason 193 yds. | CAL Donald Pearson 68 yds. |
| 2023 AFL POST SEASON SCHEDULE |
||||
| Wild Card Round | ||||
| Sat, Jan. 13 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CIN 14 at MIN 45 | Final | CIN Matt Berkley 307 yds. | MIN Darnell Sullivan 66 yds. | MIN Dominique Worthy 96 yds. |
| ATL 7 at KC 26 | Final | KC Thaddeus Lewis 262 yds. | KC Jordan Morris 89 yds. | KC J.J. Reed 130 yds. |
| Sun, Jan. 14 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| TB 17 at BAL 31 | Final | TB John Locke 229 yds. | BAL Tim Harper 79 yds. | TB Otis Glendale 76 yds. |
| LA 48 at MIA 32 | Final | MIA Adam Murray 403 yds. | LA Gary Brightwell 118 yds. | LA Jayar Jackson 151 yds. |
| PHI 23 at CLE 24 | Final | PHI Kyle Reid 367 yds. | PHI Paul Perkins 61 yds. | PHI Jaydon Thompson 181 yds. |
| Mon, Jan. 15 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| NO 9 at DAL 32 | Final | DAL Adam Froman 337 yds. | DAL Chris L. Tucker 72 yds. | NO Jacob Mallory 148 yds. |
| Divisional Round | ||||
| Sat, Jan. 20 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| DAL 10 at KC 34 | Final | DAL Adam Froman 175 yds. | KC Jordan Morris 100 yds. | DAL Marlon Williams 68 yds. |
| LA 21 at CAL 24 | Final | CAL Travis Wilson 252 yds. | LA Gary Brightwell 108 yds. | LA Jayar Jackson 83 yds. |
| Sun, Jan. 21 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| MIN 23 at BAL 31 | Final | MIN Thomas Kaye 349 yds. | BAL Tim Harper 74 yds. | MIN Dominique Worthy 147 yds. |
| CLE 27 at DET 24 | Final | CLE De'Andre Johnson 215 yds. | CLE De'Andre Johnson 97 yds. | CLE Antonio Tucker 75 yds. |
| Conference Championships | ||||
| Sun, Jan. 28 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CLE 17 at KC 10 | Final | KC Thaddeus Lewis 272 yds. | CLE De'Andre Johnson 68 yds. | CLE Antonio Tucker 116 yds. |
| BAL 31 at CAL 34 | Final | BAL Randy Carlysle 273 yds. | BAL Tim Harper 93 yds. | BAL Jonathan Adams 97 yds. |
| Super Bowl XL | ||||
| Sun, Feb. 4 | Time (ET) | Top Passer | Top Rusher | Top Receiver |
| CLE 20 at CAL 34 | Final | CAL Travis Wilson 319 yds. | CAL Micah Mason 182 yds, | CAL Jake Upton 108 yds. |